J Neurochem 114(3):820831
A drug that is right for one person could be harmful to another due to differences in health conditions, other medications, or dosing needs
Huang N, Winans T, Wyman B, Oaks Z, Faludi T, Choudhary G et al (2024) Rab4A-directed endosome traffic shapes pro-inflammatory mitochondrial metabolism in T cells via mitophagy, CD98 expression, and kynurenine-sensitive mTOR activation
A documented informed consent discussion (next section)
The methylation enzymes (BHMT, MAT) begin upregulating, but tissue SAMe levels aren't yet optimised
Figure 5 ALC reduced cholesterol synthesis by decreasing SREBP2 levels in Huh-7 hepatocytes To elucidate the cellular mechanisms underlying ALCs cholesterol-lowering effects, ALC reduced the plasma TC in mice and decreased the hepatic SREBP2 and HMGCR levels